Rabbit Polyclonal Antibody to CDC14B
货号：
P30450
别名：
Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
应用：
WB,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O60729
规格：
目录价
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Description |
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CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. |
Specification |
|
|---|---|
| Aliases | Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B |
| Entrez GeneID | 8555 |
| Swissprot | O60729 |
| WB Predicted band size | 56.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
|---|---|
| WB | 1/1000 |
| FCM | 1/10-1/50 |
Product Image
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Western blot analysis of CDC14B Antibody (Center) (Cat. #P30450) in 293 cell line lysates (35ug/lane). CDC14B (arrow) was detected using the purified Pab.
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CDC14B Antibody (Center) (Cat. #P30450) flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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