Mouse Monoclonal Antibody to BCL11B
货号:
31219
别名:
ATL1; RIT1; CTIP2; IMD49; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha
应用:
IHC,IF,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9C0K0
规格:
目录价
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Description |
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This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
References |
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1.J Immunol. 2014 Sep 1;193(5):2059-65. 2.PLoS One. 2013;8(1):e55147. |
Specification |
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Aliases | ATL1; RIT1; CTIP2; IMD49; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha |
Entrez GeneID | 64919 |
Swissprot | Q9C0K0 |
clone | 1F8G8 |
WB Predicted band size | 95.5kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human BCL11B (AA: 1-150) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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IHC | 1/200 - 1/1000 |
IF | 1/50 - 1/250 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Immunofluorescence analysis of Hela cells using BCL11B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of Hela cells using BCL11B mouse mAb (green) and negative control (red).
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Flow cytometric analysis of Jurkat cells using BCL11B mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using BCL11B mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using BCL11B mouse mAb with DAB staining.