Rabbit Polyclonal Antibody to ZRANB1
货号：
P30552
别名：
Ubiquitin thioesterase ZRANB1, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1, ZRANB1, TRABID
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UGI0
规格：
目录价
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Description |
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ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling. |
Specification |
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|---|---|
| Aliases | Ubiquitin thioesterase ZRANB1, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1, ZRANB1, TRABID |
| Entrez GeneID | 54764 |
| Swissprot | Q9UGI0 |
| WB Predicted band size | 81.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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Western blot analysis of ZRANB1 Antibody (C-term) (Cat. #P30552) in K562 cell line lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.
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Western blot analysis of ZRANB1 Antibody (C-term) (Cat. #P30552) in mouse cerebellum tissue lysates (35ug/lane). ZRANB1 (arrow) was detected using the purified Pab.
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ZRANB1 Antibody (C-term) (Cat. #P30552) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZRANB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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