Mouse Monoclonal Antibody to BCL2L10
货号：
31214
别名：
Boo; Diva; BCL-B; bcl2-L-10
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9HD36
规格：
目录价
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Description |
|---|
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. |
References |
|---|
| 1.Hum Reprod. 2013 Mar;28(3):729-39. 2.Oncotarget. 2012 Apr;3(4):490-501. |
Specification |
|
|---|---|
| Aliases | Boo; Diva; BCL-B; bcl2-L-10 |
| Entrez GeneID | 10017 |
| Swissprot | Q9HD36 |
| clone | 8A11G12 |
| WB Predicted band size | 22kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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