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Mouse Monoclonal Antibody to CHRNA3
货号: 31232
别名: LNCR2; PAOD2; NACHRA3
应用: IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P32297
规格:
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Description

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

References

1.Tumour Biol. 2015 Jul;36(7):4987-92.
2.Int J Mol Sci. 2014 Mar 28;15(4):5446-57.

Specification

Aliases LNCR2; PAOD2; NACHRA3
Entrez GeneID 1136
Swissprot P32297
clone 6D3A10
WB Predicted band size 57.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CHRNA3 (AA: 32-240) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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