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Rabbit Polyclonal Antibody to CLDN7
货号: P30734
别名: Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2
应用: WB,IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: O95471
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Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.

Specification

Aliases Claudin-7, CLDN-7, CLDN7, CEPTRL2, CPETRL2
Entrez GeneID 1366
Swissprot O95471
WB Predicted band size 22.4kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This CLDN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human CLDN7.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000
IHC 1/100-1/500
FCM 1/10-1/50
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