Rabbit Polyclonal Antibody to ENSA
货号：
P30787
别名：
Alpha-endosulfine, ARPP-19e, ENSA
应用：
WB,FCM
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
O43768
规格：
目录价
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Description |
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ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. |
Specification |
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|---|---|
| Aliases | Alpha-endosulfine, ARPP-19e, ENSA |
| Entrez GeneID | 2029 |
| Swissprot | O43768 |
| WB Predicted band size | 13.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This ENSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human ENSA. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/1000 |
| FCM | 1/10-1/50 |
Product Image
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ENSA Antibody (Center) (Cat. #P30787) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ENSA antibody detected the ENSA protein (arrow).
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ENSA Antibody (Center) (Cat. #P30787) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the ENSA antibody detected the ENSA protein (arrow).
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ENSA Antibody (Center) (Cat. #P30787) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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