Mouse Monoclonal Antibody to BAG1
货号:
31237
别名:
HAP; BAG-1; RAP46
应用:
FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q99933
规格:
目录价
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Description |
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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. |
References |
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1.Oncol Rep. 2014 Oct;32(4):1441-6. 2.Cell Physiol Biochem. 2014;33(2):365-74. |
Specification |
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Aliases | HAP; BAG-1; RAP46 |
Entrez GeneID | 573 |
Swissprot | Q99933 |
clone | 2F7A11 |
WB Predicted band size | 38.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human BAG1 (AA: 219-346) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |