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Mouse Monoclonal Antibody to BAG1
货号: 31237
别名: HAP; BAG-1; RAP46
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q99933
规格:
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Description

The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

References

1.Oncol Rep. 2014 Oct;32(4):1441-6.
2.Cell Physiol Biochem. 2014;33(2):365-74.

Specification

Aliases HAP; BAG-1; RAP46
Entrez GeneID 573
Swissprot Q99933
clone 2F7A11
WB Predicted band size 38.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human BAG1 (AA: 219-346) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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