Rabbit Polyclonal Antibody to GUCY2D
货号:
P30973
别名:
Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
应用:
WB,IHC,FCM
反应种属:
Human, Mouse, Rat
抗体类型:
Primary antibody
Swissprot:
Q02846
规格:
目录价
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Description |
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This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]. |
Specification |
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Aliases | Retinal guanylyl cyclase 1, RETGC-1, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC, GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1 |
Entrez GeneID | 3000 |
Swissprot | Q02846 |
WB Predicted band size | 120.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | This GUCY2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-570 amino acids from the Central region of human GUCY2D. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/1000 |
IHC | 1/100-1/500 |
FCM | 1/10-1/50 |
Product Image
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GUCY2D Antibody (Center) (Cat. #P30973) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the GUCY2D antibody detected the GUCY2D protein (arrow).
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GUCY2D Antibody (Center) (Cat. #P30973) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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GUCY2D Antibody (Center) (Cat. #P30973)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GUCY2D Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.