Rabbit Polyclonal Antibody to EDN1
货号:
P31023
别名:
Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1
应用:
WB,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P05305
规格:
目录价
在线咨询
Description |
---|
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. |
Specification |
|
---|---|
Aliases | Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1 |
Entrez GeneID | 1906 |
Swissprot | P05305 |
WB Predicted band size | 24.4kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human EDN1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/1000 |
IHC | 1/100-1/500 |
IF | 1/10-1/50 |
Product Image
-
EDN1 Antibody (C-term) (Cat. #P31023) western blot analysis in ZR-75-1,U251,MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the EDN1 antibody detected the EDN1 protein (arrow).
-
Confocal immunofluorescent analysis of EDN1 Antibody (C-term)(Cat#P31023) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
-
EDN1 Antibody (C-term) (Cat. #P31023)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EDN1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.