Rabbit Polyclonal Antibody to DAZ3
货号:
P31066
别名:
Deleted in azoospermia protein 3, DAZ3
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9NR90
规格:
目录价
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Description |
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This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. |
Specification |
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Aliases | Deleted in azoospermia protein 3, DAZ3 |
Entrez GeneID | 57054 |
Swissprot | Q9NR90 |
WB Predicted band size | 55.0kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This DAZ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/1000 |
IHC | 1/100-1/500 |
Product Image
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DAZ3 Antibody (C-term) (Cat. #P31066) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DAZ3 antibody detected the DAZ3 protein (arrow).
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DAZ3 Antibody (C-term) (Cat. #P31066)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DAZ3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.