Rabbit Polyclonal Antibody to SEC62 (N-term)
货号：
P31176
别名：
Translocation protein SEC62, Translocation protein 1, TP-1, hTP-1, SEC62, TLOC1
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99442
规格：
目录价
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Description |
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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. |
Specification |
|
|---|---|
| Aliases | Translocation protein SEC62, Translocation protein 1, TP-1, hTP-1, SEC62, TLOC1 |
| Entrez GeneID | 7095 |
| Swissprot | Q99442 |
| WB Predicted band size | 45.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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SEC62 Antibody (N-term) (Cat. #P31176) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SEC62 antibody detected the SEC62 protein (arrow).
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SEC62 Antibody (N-term) (Cat. #P31176)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEC62 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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