Rabbit Polyclonal Antibody to CD320
货号：
P31222
别名：
CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, FDC-SM-8D6, Transcobalamin receptor, TCblR, CD320, CD320, 8D6A
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NPF0
规格：
目录价
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Description |
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The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]). |
Specification |
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|---|---|
| Aliases | CD320 antigen, 8D6 antigen, FDC-signaling molecule 8D6, FDC-SM-8D6, Transcobalamin receptor, TCblR, CD320, CD320, 8D6A |
| Entrez GeneID | 51293 |
| Swissprot | Q9NPF0 |
| WB Predicted band size | 29.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
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