Mouse Monoclonal Antibody to HTR3B
货号:
31295
别名:
5-HT3B
应用:
WB,IF,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O95264
规格:
目录价
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Description |
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The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. |
References |
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1.Yonsei Med J. 2015 Sep;56(5):1415-20. 2.Psychiatry Res. 2014 Sep 30;219(1):235-7. |
Specification |
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Aliases | 5-HT3B |
Entrez GeneID | 9177 |
Swissprot | O95264 |
clone | 2H9H5 |
WB Predicted band size | 50.3kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human HTR3B (AA: extra 23-150) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IF | 1/100 - 1/500 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Western blot analysis using HTR3B mouse mAb against SK-N-SH (1) and Hela (2) cell lysate.
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Immunofluorescence analysis of Hela cells using HTR3B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of Hela cells using HTR3B mouse mAb (green) and negative control (red).