Rabbit Polyclonal Antibody to CIDEA
货号:
P31390
别名:
Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A, CIDEA
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O60543
规格:
目录价
在线咨询
Description |
---|
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified. |
Specification |
|
---|---|
Aliases | Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A, CIDEA |
Entrez GeneID | 1149 |
Swissprot | O60543 |
WB Predicted band size | 24.7kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CIDEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/1000 |