Rabbit Polyclonal Antibody to CSTA
货号:
P31452
别名:
Cystatin-A, Cystatin-AS, Stefin-A, Cystatin-A, N-terminally processed, CSTA, STF1, STFA
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P01040
规格:
目录价
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Description |
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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. |
Specification |
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Aliases | Cystatin-A, Cystatin-AS, Stefin-A, Cystatin-A, N-terminally processed, CSTA, STF1, STFA |
Entrez GeneID | 1475 |
Swissprot | P01040 |
WB Predicted band size | 11.0kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CSTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the C-terminal region of human CSTA. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/1000 |
IHC | 1/100-1/500 |
Product Image
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CSTA Antibody (C-term) (Cat. #P31452) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CSTA antibody detected the CSTA protein (arrow).
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Western blot analysis of CSTA (arrow) using rabbit polyclonal CSTA Antibody (C-term) (Cat. #P31452). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CSTA gene.
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CSTA Antibody (C-term) (P31452)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSTA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.