Rabbit Polyclonal Antibody to QPRT
货号：
P31459
别名：
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15274
规格：
目录价
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Description |
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This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. |
Specification |
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|---|---|
| Aliases | Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT |
| Entrez GeneID | 23475 |
| Swissprot | Q15274 |
| WB Predicted band size | 30.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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QPRT Antibody (C-term) (Cat. #P31459) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the QPRT antibody detected the QPRT protein (arrow).
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QPRT Antibody (C-term) (P31459)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of QPRT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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