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Mouse Monoclonal Antibody to CD269
货号: 31322
别名: BCMA; TNFRSF17; BCM; TNFRSF13A
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q02223
规格:
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Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

References

1.Lupus. 2016 May;25(6):582-92.
2.Crit Rev Immunol. 2012;32(4):287-305.

Specification

Aliases BCMA; TNFRSF17; BCM; TNFRSF13A
Entrez GeneID 608
Swissprot Q02223
clone 1D12G9
WB Predicted band size 20.2kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human BCMA (AA: QMAGQCSQNEYFDSLc) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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