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Mouse Monoclonal Antibody to BCL6
货号: 31318
别名: BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
应用: IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P41182
规格:
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Description

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

References

1.Cancer Lett. 2015 Sep 1;365(2):190-200.
2.BMC Cancer. 2014 Jun 10;14:418.

Specification

Aliases BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
Entrez GeneID 604
Swissprot P41182
clone 2G1B6
WB Predicted band size 78.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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