Rabbit Polyclonal Antibody to EPOR
货号：
P31676
别名：
Erythropoietin receptor, EPO-R, EPOR
应用：
WB,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P19235
规格：
目录价
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Description |
|---|
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. |
Specification |
|
|---|---|
| Aliases | Erythropoietin receptor, EPO-R, EPOR |
| Entrez GeneID | 2057 |
| Swissprot | P19235 |
| WB Predicted band size | 55.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/1000 |
| IF | 1/10-1/50 |
| FCM | 1/10-1/50 |
Product Image
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EPOR Antibody (Center) (Cat. #P31676) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the EPOR antibody detected the EPOR protein (arrow).
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Confocal immunofluorescent analysis of EPOR Antibody (Center)(Cat#P31676) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
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EPOR Antibody (Center) (Cat. #P31676) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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