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Mouse Monoclonal Antibody to CD152
货号: 31352
别名: CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P16410
规格:
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Description

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

References

1.Asian Pac J Cancer Prev. 2016;17(8):3785-91.
2.Eur J Cancer. 2015 Nov;51(17):2689-97.

Specification

Aliases CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3
Entrez GeneID 1493
Swissprot P16410
clone 8B3F8
WB Predicted band size 24.6kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD152 (AA: extra 36-161) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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