Rabbit Polyclonal Antibody to Mouse Tbk1 (N-term)
货号：
P31778
别名：
Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q9WUN2
规格：
目录价
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Description |
|---|
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response. |
Specification |
|
|---|---|
| Aliases | Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1 |
| Entrez GeneID | 56480 |
| Swissprot | Q9WUN2 |
| WB Predicted band size | 83.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This Mouse Tbk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/1000 |
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