Mouse Monoclonal Antibody to CD134
货号：
31363
别名：
TNFRSF4; OX40; ACT35; IMD16; TXGP1L
应用：
IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P43489
规格：
目录价
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Description |
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
References |
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| 1.Oncotarget. 2015 Nov 10;6(35):37588-99. 2.Hepatology. 2014 Nov;60(5):1494-507. |
Specification |
|
|---|---|
| Aliases | TNFRSF4; OX40; ACT35; IMD16; TXGP1L |
| Entrez GeneID | 7293 |
| Swissprot | P43489 |
| clone | 3G5G7 |
| WB Predicted band size | 29.3kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD134 (AA: extra 29-214) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of HL-60 cells using CD134 mouse mAb (green) and negative control (red).
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Flow cytometric analysis of Jurkat cells using CD134 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD134 mouse mAb with DAB staining.
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