Rabbit Polyclonal Antibody to EIF2S3L
货号:
P32127
别名:
Putative eukaryotic translation initiation factor 2 subunit 3-like protein, Eukaryotic translation initiation factor 2 subunit gamma A, eIF-2-gamma A, eIF-2gA, EIF2S3L
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q2VIR3
规格:
目录价
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Description |
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eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B (By similarity). |
Specification |
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Aliases | Putative eukaryotic translation initiation factor 2 subunit 3-like protein, Eukaryotic translation initiation factor 2 subunit gamma A, eIF-2-gamma A, eIF-2gA, EIF2S3L |
Swissprot | Q2VIR3 |
WB Predicted band size | 51.2kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This EIF2S3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-299 amino acids from the Central region of human EIF2S3L. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/1000 |