Rabbit Polyclonal Antibody to POLK
货号：
P32331
别名：
DNA polymerase kappa, DINB protein, DINP, POLK, DINB1
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UBT6
规格：
目录价
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Description |
|---|
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]). |
Specification |
|
|---|---|
| Aliases | DNA polymerase kappa, DINB protein, DINP, POLK, DINB1 |
| Entrez GeneID | 51426 |
| Swissprot | Q9UBT6 |
| WB Predicted band size | 98.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This POLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human POLK. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
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