Rabbit Polyclonal Antibody to Mouse Mavs (N-term)
货号：
P32350
别名：
Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Virus-induced-signaling adapter, VISA, Mavs, Ips1, Visa
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q8VCF0
规格：
目录价
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Description |
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Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity). |
Specification |
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|---|---|
| Aliases | Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Virus-induced-signaling adapter, VISA, Mavs, Ips1, Visa |
| Entrez GeneID | 228607 |
| Swissprot | Q8VCF0 |
| WB Predicted band size | 53.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/1000 |
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