Rabbit Polyclonal Antibody to UBR1 (N-term)
货号:
P32369
别名:
E3 ubiquitin-protein ligase UBR1, 632-, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I, UBR1
应用:
WB
反应种属:
Mouse
抗体类型:
Primary antibody
Swissprot:
Q8IWV7
规格:
目录价
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Description |
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The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. |
Specification |
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Aliases | E3 ubiquitin-protein ligase UBR1, 632-, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I, UBR1 |
Entrez GeneID | 197131 |
Swissprot | Q8IWV7 |
WB Predicted band size | 200.2kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Mouse |
Immunogen | This UBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human UBR1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/1000 |