Rabbit Polyclonal Antibody to Phospho-mouse TSC1(S1138)
货号：
P32443
别名：
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q9EP53
规格：
目录价
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Description |
|---|
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). |
Specification |
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|---|---|
| Aliases | Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243 |
| Entrez GeneID | 64930 |
| Swissprot | Q9EP53 |
| WB Predicted band size | 128.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1138 of mouse TSC1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | DB: 1/500 |
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