Rabbit Polyclonal Antibody to TSC1 (Center T417)
货号：
P32463
别名：
Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q92574
规格：
目录价
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Description |
|---|
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
Specification |
|
|---|---|
| Aliases | Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC |
| Entrez GeneID | 7248 |
| Swissprot | Q92574 |
| WB Predicted band size | 129.8kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/1000 |
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