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Mouse Monoclonal Antibody to FOLR1
货号: 31396
别名: FBP; FOLR
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P15328
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Description

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

References

1.Biosens Bioelectron. 2016 Apr 15;78:147-53.
2.PLoS One. 2015 Mar 27;10(3):e0122209.

Specification

Aliases FBP; FOLR
Entrez GeneID 2348
Swissprot P15328
clone 3G12B7
WB Predicted band size 29.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human FOLR1 (AA: 41-227) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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