Mouse Monoclonal Antibody to CDKN1B
货号：
P32632
别名：
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P46527
规格：
目录价
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Description |
|---|
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. |
Specification |
|
|---|---|
| Aliases | Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1 |
| Entrez GeneID | 1027 |
| Swissprot | P46527 |
| WB Predicted band size | 22.1kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CDKN1B antibody is generated from a mouse immunized with CDKN1B recombinant protein. |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
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Western blot analysis of lysates from MCF-7, U266 cell line (from left to right), using CDKN1B Antibody(Cat. #P32632). P32632 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35μg per lane.
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Immunohistochemical analysis of paraffin-embedded H. skeletal muscle section using CDKN1B Antibody(Cat#P32632). P32632 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-mouse IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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