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Rabbit Polyclonal Antibody to HUMAN-RIN1(Y36)
货号: P32772
别名: Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q13671
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Description

Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Specification

Aliases Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, RIN1
Entrez GeneID 9610
Swissprot Q13671
WB Predicted band size 84.1kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-70 amino acids from human.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000
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