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Rabbit Polyclonal Antibody to (Mouse) Sox17
货号: P32807
别名: Transcription factor SOX-17, Sox17, Sox-17
应用: WB
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q61473
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Description

Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

Specification

Aliases Transcription factor SOX-17, Sox17, Sox-17
Entrez GeneID 20671
Swissprot Q61473
WB Predicted band size 44.6kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen This (Mouse) Sox17 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of human (Mouse) Sox17.

Application

WB 1/1000
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