Rabbit Polyclonal Antibody to Mouse Hes1
货号：
P32837
别名：
Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1
应用：
WB
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P35428
规格：
目录价
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Description |
|---|
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). |
Specification |
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|---|---|
| Aliases | Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1 |
| Entrez GeneID | 15205 |
| Swissprot | P35428 |
| WB Predicted band size | 29.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1. |
Application |
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|---|---|
| WB | 1/1000 |
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