Rabbit Polyclonal Antibody to PPP2R5B
货号：
P32853
别名：
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta, PPP2R5B
应用：
WB,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15173
规格：
目录价
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Description |
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The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues. |
Specification |
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|---|---|
| Aliases | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta, PPP2R5B |
| Entrez GeneID | 5526 |
| Swissprot | Q15173 |
| WB Predicted band size | 57.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B. |
Application |
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|---|---|
| WB | 1/1000 |
| IF | 1/25 |
Product Image
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Western blot analysis of lysate from SK-N-MC cell line, using PPP2R5B Antibody (C-term)(Cat. #P32853). P32853 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
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Fluorescent image of SH-SY5Y cells stained with PPP2R5B Antibody (C-term)(Cat#P32853). P32853 was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
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