Rabbit Polyclonal Antibody to PRDM14 (N-term)
货号：
P32921
别名：
PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9GZV8
规格：
目录价
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Description |
|---|
Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'. |
Specification |
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|---|---|
| Aliases | PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14 |
| Entrez GeneID | 63978 |
| Swissprot | Q9GZV8 |
| WB Predicted band size | 64.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This PRDM14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 128-163 amino acids from the N-terminal region of human PRDM14. |
Application |
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|---|---|
| WB | 1/1000 |
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