Rabbit Polyclonal Antibody to (Mouse) Sox2 (N-term)
货号:
P32996
别名:
Transcription factor SOX-2, Sox2, Sox-2
应用:
WB
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P48432
规格:
目录价
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Description |
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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
Specification |
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Aliases | Transcription factor SOX-2, Sox2, Sox-2 |
Entrez GeneID | 20674 |
Swissprot | P48432 |
WB Predicted band size | 34.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This Mouse Sox2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of mouse Sox2. |
Application |
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WB | 1/1000 |