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Mouse Monoclonal Antibody to PTPRD
货号: 31467
别名: HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P23468
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Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.

References

1.Acta Paediatr. 2016 Mar;105(3):e132-41.2.Cancer Invest. 2012 Jun;30(5):422-32.

Specification

Aliases HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA
Entrez GeneID 5789
Swissprot P23468
clone 5H5D7
WB Predicted band size 214.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PTPRD (AA: extra 1077-1265) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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