Rabbit Polyclonal Antibody to KDM6A
货号：
P33078
别名：
Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein, KDM6A, UTX
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O15550
规格：
目录价
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Description |
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Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. |
Specification |
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|---|---|
| Aliases | Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein, KDM6A, UTX |
| Entrez GeneID | 7403 |
| Swissprot | O15550 |
| WB Predicted band size | 154.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This KDM6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 797-832 amino acids from the Central region of human KDM6A. |
Application |
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|---|---|
| WB | 1/2000 |
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