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Mouse Monoclonal Antibody to TIGIT
货号: 31514
别名: VSIG9; VSTM3; WUCAM
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q495A1
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Description

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.

References

1.Clin Cancer Res. 2016 Jun 15;22(12):3057-66.
2.Eur J Immunol. 2015 Oct;45(10):2886-97.

Specification

Aliases VSIG9; VSTM3; WUCAM
Entrez GeneID 201633
Swissprot Q495A1
clone 4C5B9
WB Predicted band size 26.3kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TIGIT (AA: extra 22-141) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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