Rabbit Polyclonal Antibody to SDR
货号:
P33455
别名:
Serum deprivation-response protein, Cavin-2, PS-p68, Phosphatidylserine-binding protein, SDPR {ECO:0000312|EMBL:AAD177951}
应用:
WB,IHC,FCM
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
O95810
规格:
目录价
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Description |
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This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. |
Specification |
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Aliases | Serum deprivation-response protein, Cavin-2, PS-p68, Phosphatidylserine-binding protein, SDPR {ECO:0000312|EMBL:AAD177951} |
Entrez GeneID | 8436 |
Swissprot | O95810 |
WB Predicted band size | 47.2kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This SDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human SDR. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
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WB | 1/1000 |
IHC | 1/100-1/500 |
FCM | 1/10-1/50 |
Product Image
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Anti-SDR Antibody (Center) at 1:1000 dilution + human heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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SDR Antibody (Center) (Cat. #P33455) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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SDR Antibody (Center) (Cat. #P33455) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SDR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.