Rabbit Polyclonal Antibody to LRPPRC
货号：
P33500
别名：
Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130
应用：
WB
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P42704
规格：
目录价
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Description |
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May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity). |
Specification |
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|---|---|
| Aliases | Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130 |
| Entrez GeneID | 10128 |
| Swissprot | P42704 |
| WB Predicted band size | 157.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC. |
Application |
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|---|---|
| WB | 1/2000 |
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