Rabbit Polyclonal Antibody to YES1 (N-term)
货号:
P33580
别名:
Tyrosine-protein kinase Yes, Proto-oncogene c-Yes, p61-Yes, YES1, YES
应用:
WB,IHC
反应种属:
Human, Mouse
抗体类型:
Primary antibody
Swissprot:
P07947
规格:
目录价
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Description |
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YES is a member of the Src family of non-receptor tyrosine kinases participating in a wide range of cellular signalling pathways. The gene that encodes YES is the cellular homolog of the Yamaguchi sarcoma virus oncogene. This gene lies in proximity to thymidylate synthase gene on chromosome 18, and a pseudogene of it has mapped to chromosome 22. |
Specification |
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Aliases | Tyrosine-protein kinase Yes, Proto-oncogene c-Yes, p61-Yes, YES1, YES |
Entrez GeneID | 7525 |
Swissprot | P07947 |
WB Predicted band size | 60.8kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This YES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human YES1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/1000 |
IHC | 1/100-1/500 |
Product Image
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Anti-YES Antibody (K11) at 1:1000 dilution + MDA-MB-468 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 61 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.