Rabbit Polyclonal Antibody to FIBG
货号：
P33649
别名：
Fibrinogen gamma chain, FGG
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P02679
规格：
目录价
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Description |
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FIBG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. |
Specification |
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|---|---|
| Aliases | Fibrinogen gamma chain, FGG |
| Entrez GeneID | 2266 |
| Swissprot | P02679 |
| WB Predicted band size | 51.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This FIBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human FIBG. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
| IF | 1/10-1/50 |
Product Image
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Anti-FIBG Antibody (C-term) at 1:4000 dilution + A431 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Western blot analysis of FIBG Antibody (C-term) (Cat. #P33649) in NCI-H460 cell line lysates (35ug/lane). FIBG (arrow) was detected using the purified Pab.
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Confocal immunofluorescent analysis of FIBG Antibody (C-term)(Cat#P33649) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
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FIBG Antibody (C-term) (Cat. #P33649) IHC analysis in formalin fixed and paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FIBG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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