Rabbit Polyclonal Antibody to TESK2 (Center C225)
货号：
P33870
别名：
Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q96S53
规格：
目录价
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Description |
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TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells. |
Specification |
|
|---|---|
| Aliases | Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2 |
| Entrez GeneID | 10420 |
| Swissprot | Q96S53 |
| WB Predicted band size | 63.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human TESK2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 |
| IHC | 1/100-1/500 |
Product Image
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Anti-TESK2 Antibody (Center) at 1:500 dilution + HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Formalin-fixed and paraffin-embedded human testis tissue reacted with TESK2 antibody (Center)(Cat.#AP7812f), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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