产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Mouse Monoclonal Antibody to LRP6
货号: 31564
别名: ADCAD2; STHAG7
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: O75581
规格:
目录价
在线咨询

Description

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

References

1.Cancer Biomark. 2017;19(2):151-159.
2.Int J Med Sci. 2014 May 2;11(7):685-90.

Specification

Aliases ADCAD2; STHAG7
Entrez GeneID 4040
Swissprot O75581
clone 1A3F5
WB Predicted band size 180kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human LRP6 (AA: extra 1198-1370) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852