Mouse Monoclonal Antibody to CD363
货号：
31546
别名：
S1PR1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; D1S3362
应用：
WB,IHC,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P21453
规格：
目录价
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Description |
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The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. |
References |
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| 1.J R Soc Interface. 2016 Dec;13(125). pii: 20160823. 2.Eur J Cancer. 2015 Sep;51(14):1937-45. |
Specification |
|
|---|---|
| Aliases | S1PR1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; D1S3362 |
| Entrez GeneID | 1901 |
| Swissprot | P21453 |
| clone | 8E4H5 |
| WB Predicted band size | 42.8kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD363 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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|---|---|
| WB | 1/500 - 1/2000 |
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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Flow cytometric analysis of HL-60 cells using CD363 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD363 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using CD363 mouse mAb with DAB staining.
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