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Mouse Monoclonal Antibody to MLL3
货号: P33966
别名: Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, 2.1.1.43, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, KMT2C, HALR, KIAA1506, MLL3
应用: WB
反应种属: Human, Mouse
抗体类型: Primary antibody
Swissprot: Q8NEZ4
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Description

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

Specification

Aliases Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, 2.1.1.43, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, KMT2C, HALR, KIAA1506, MLL3
Entrez GeneID 58508
Swissprot Q8NEZ4
WB Predicted band size 541.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen This MLL3 antibody is generated from a mouse immunized with a recombinant protein of human MLL3.
Formulation Purified antibody in TBS with 0.05% sodium azide.

Application

WB 1/2000
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