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Mouse Monoclonal Antibody to CD344
货号: 31572
别名: FZD4; Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; FZD4S
应用: FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9ULV1
规格:
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Description

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

References

1.Ophthalmic Genet. 2017 Jul-Aug;38(4):380-382.
2.Mol Pharmacol. 2016 Oct;90(4):447-59.

Specification

Aliases FZD4; Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; FZD4S
Entrez GeneID 8322
Swissprot Q9ULV1
clone 2F3A7
WB Predicted band size 60kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD344 (AA: extra 37-222) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000
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