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Mouse Monoclonal Antibody to CD169
货号: 31583
别名: SIGLEC1; SN; SIGLEC-1; dJ1009E24.1
应用: IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q9BZZ2
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Description

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.

References

1.J Virol. 2017 Oct 13;91(21). pii: e00972-17.
2.Cancer Sci. 2017 Mar;108(3):290-295.

Specification

Aliases SIGLEC1; SN; SIGLEC-1; dJ1009E24.1
Entrez GeneID 6614
Swissprot Q9BZZ2
clone 2A4D1
WB Predicted band size 182.6kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD169 (AA: extra 20-197) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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